Standard

Diastolic blood pressure

WNT9A · rs4653889

Where this position leads

Condition: Blood Pressure

rs4653889 Condition: Blood Pressure Blood Pressure Condition rs4653889 rs4653889 WNT9A

What the study found

Who was studied 295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.152 higher; p = 1 × 10−10.

Where it sits Chromosome 1, band 1q42.13 — in an intron of WNT9A.

What each result means

A/A Two copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
G/G No copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs4653889

What is rs4653889?

rs4653889 is a single position in the genome, in or near the WNT9A gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4653889 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs4653889 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4653889 come from?

GWAS Catalog, Nature genetics 2017, PMID:27841878. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diastolic blood pressure (rs4653889). MyGeneLog™. https://www.mygenelog.com/variants/rs4653889

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