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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 4,492 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.148 higher (95% confidence interval 0.1-0.19); p = 1 × 10−10.
Where it sits Chromosome 1, band 1q42.11 — between genes, 15.2 kb from DEGS1.
What each result means
A/ANo copy of the version the research linked to Phosphatidylcholine (36:0) levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Phosphatidylcholine (36:0) levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Phosphatidylcholine (36:0) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2022 · PMID 35668104 · open access
Questions about rs4653568
What is rs4653568?
rs4653568 is a single position in the genome, in or near the near DEGS1 gene. Published research associates it with phosphatidylcholine (36:0) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4653568 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4653568 come from?
GWAS Catalog, Nature communications 2022, PMID:35668104. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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