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Number of sexual partners in opposite-sex sexual behavior

KPNA2 · rs4638

What the study found

Who was studied 358,426 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.129 higher (95% confidence interval 0.084-0.174); p = 2 × 10−8.

How common The A allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 17, band 17q24.2 — a synonymous change in KPNA2.

What each result means

A/A Two copies of the version the research linked to Number of sexual partners in opposite-sex sexual behavior. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Number of sexual partners in opposite-sex sexual behavior. That is a smaller link than two copies.
G/G No copy of the version the research linked to Number of sexual partners in opposite-sex sexual behavior. This is the starting point the study compared everyone against.
Source

Questions about rs4638

What is rs4638?

rs4638 is a single position in the genome, in or near the KPNA2 gene. Published research associates it with number of sexual partners in opposite-sex sexual behavior. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4638 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4638 come from?

GWAS Catalog, Nature human behaviour 2021, PMID:34426668. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Number of sexual partners in opposite-sex sexual behavior (rs4638). MyGeneLog™. https://www.mygenelog.com/variants/rs4638

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