1 282216123110Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,109 Japanese ancestry cases, 11,140 Japanese ancestry controls; replicated in 2,223 East Asian ancestry cases, 4,724 East Asian ancestry controls.
The effect
Each copy of the A allele carried 1.24 times the odds of Adolescent idiopathic scoliosis (95% confidence interval 1.16-1.34); p = 3 × 10−9.
How common The A allele had a frequency of about 34% in the people studied.
Where it sits Chromosome 6, band 6q24.2 — between genes, 26.6 kb from ADGRG6.
What each result means
A/ATwo copies of the version the research linked to Adolescent idiopathic scoliosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Adolescent idiopathic scoliosis. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Adolescent idiopathic scoliosis. This is the starting point the study compared everyone against.
American journal of human genetics · 2015 · PMID 26211971
Questions about rs4637667
What is rs4637667?
rs4637667 is a single position in the genome, in or near the GPR126 gene. Published research associates it with adolescent idiopathic scoliosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4637667 linked to?
On MyGeneLog this position is linked to Adolescent Idiopathic Scoliosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs4637667 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4637667 come from?
GWAS Catalog, Am J Hum Genet 2015, PMID:26211971. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 282216123110Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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