3 21171237Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI7Microsoft · Copilot1Amazon2Apple3Others7Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 88,192 cases, 162,544 controls; replicated in 34,541 cases, 261,984 controls.
The effect
Each copy of the T allele shifted the measure 0.129 higher (95% confidence interval 0.1-0.15); p = 1 × 10−25.
How common The T allele had a frequency of about 92% in the people studied.
Where it sits Chromosome 1, band 1p32.2 — in an intron of PLPP3.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Coronary artery disease — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Coronary artery disease.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Coronary artery disease compared to the general population.
Circulation research · 2018 · PMID 29212778 · open access
Questions about rs4634932
What is rs4634932?
rs4634932 is a single position in the genome, in or near the PPAP2B gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4634932 linked to?
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs4634932 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4634932 come from?
GWAS Catalog, Circ Res 2017, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 21171237Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI7Microsoft · Copilot1Amazon2Apple3Others7Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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