Standard

Caffeine consumption from coffee

TMEM56 · rs4615895

What the study found

Who was studied 373,522 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.017 lower (95% confidence interval 0.012-0.022); p = 9 × 10−11.

How common The G allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 1, band 1p21.3 — between genes, 26.8 kb from LINC02607.

What each result means

A/A No copy of the version the research linked to Caffeine consumption from coffee. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Caffeine consumption from coffee. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Caffeine consumption from coffee. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4615895

What is rs4615895?

rs4615895 is a single position in the genome, in or near the TMEM56 gene. Published research associates it with caffeine consumption from coffee. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4615895 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4615895 come from?

GWAS Catalog, Journal of the American Heart Association 2020, PMID:33287642. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Caffeine consumption from coffee (rs4615895). MyGeneLog™. https://www.mygenelog.com/variants/rs4615895

← See all variants