Standard

Body mass index

near TIAL1P1 · rs4615388

Where this position leads

Conditions: Obesity and Body Weight, Childhood Body Mass Index

rs4615388 Condition: Obesity and Body Weight Obesity and Body Weight Condition Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs4615388 rs4615388 near TIAL1P1

What the study found

Who was studied 1,122,049 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0221 lower (95% confidence interval 0.019-0.026); p = 9 × 10−34.

Where it sits Chromosome 6, band 6p12.3 — between genes, 103.1 kb from TIAL1P1.

What each result means

A/A No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4615388

What is rs4615388?

rs4615388 is a single position in the genome, in or near the near TIAL1P1 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4615388 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight, Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs4615388 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4615388 come from?

GWAS Catalog, Nature communications 2022, PMID:36581621. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs4615388). MyGeneLog™. https://www.mygenelog.com/variants/rs4615388

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