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Who was studied 3,230 European ancestry cases, 4,829 European ancestry controls; replicated in 1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls.
The effect
Each copy of the C allele carried 1.32 times the odds of Crohn's disease; p = 7 × 10−27.
How common The C allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 5, band 5p13.1 — between genes, 2.8 kb from LOC124900967.
What each result means
C/CTwo copies of the version the research linked to Crohn's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Crohn's disease. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Crohn's disease. This is the starting point the study compared everyone against.
rs4613763 is a single position in the genome, in or near the PTGER4 gene. Published research associates it with crohn's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4613763 linked to?
On MyGeneLog this position is linked to Crohn's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs4613763 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4613763 come from?
GWAS Catalog, Nat Genet 2008, PMID:18587394. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 303211622238Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others8Total30Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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