0 282721115Reads by AI crawlersClaude2ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot7Amazon2Apple1China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others15Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied at least 71,880 European ancestry cases, at least 383,378 European ancestry controls (MTAG boosted by 113,578 carotid intima-media thickness samples).
The effect
Each copy of the T allele shifted the measure 0.0214 lower (95% confidence interval 0.017-0.026); p = 1 × 10−24.
Where it sits Chromosome 19, band 19q13.32 — between genes, 10.9 kb from NECTIN2.
What each result means
C/CNo copy of the version the research linked to Alzheimer's disease (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Alzheimer's disease (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Alzheimer's disease (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39537608 · open access
Questions about rs4605275
What is rs4605275?
rs4605275 is a single position in the genome, in or near the near NECTIN2 gene. Published research associates it with alzheimer's disease (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4605275 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs4605275 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4605275 come from?
GWAS Catalog, Nature communications 2024, PMID:39537608. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 282721115Reads by AI crawlersClaude2ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot7Amazon2Apple1China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others15Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.