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Who was studied 510,795 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.053 lower (95% confidence interval 0.036-0.07); p = 4 × 10−10.
How common The A allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 12, band 12q14.1 — between genes, 212.2 kb from Y_RNA.
What each result means
A/ATwo copies of the version the research linked to Noncognitive aspects of educational attainment. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Noncognitive aspects of educational attainment. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Noncognitive aspects of educational attainment. This is the starting point the study compared everyone against.
Nature genetics · 2021 · PMID 33414549 · open access
Questions about rs4581486
What is rs4581486?
rs4581486 is a single position in the genome, in or near the near Y_RNA gene. Published research associates it with noncognitive aspects of educational attainment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4581486 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does having rs4581486 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4581486 come from?
GWAS Catalog, Nature genetics 2021, PMID:33414549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Noncognitive aspects of educational attainment (rs4581486). MyGeneLog™. https://www.mygenelog.com/variants/rs4581486