Sensitive

Squamous cell lung carcinoma

MORN5 · rs4573350

Where this position leads

Condition: Lung Squamous Cell Carcinoma

rs4573350 Condition: Lung Squamous Cell Carcinoma Lung Squamous Cell Carcinoma Condition rs4573350 rs4573350 MORN5

What the study found

Who was studied 8,350 Chinese or European ancestry cases, 27,355 Chinese or European ancestry controls.

The effect Each copy of the T allele carried 1.13 times the odds of Squamous cell lung carcinoma (95% confidence interval 1.09-1.18); p = 3 × 10−9.

Where it sits Chromosome 9, band 9q33.2 — in an intron of MORN5.

What each result means

C/C No copy of the version the research linked to Squamous cell lung carcinoma. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Squamous cell lung carcinoma. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Squamous cell lung carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4573350

What is rs4573350?

rs4573350 is a single position in the genome, in or near the MORN5 gene. Published research associates it with squamous cell lung carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4573350 linked to?

On MyGeneLog this position is linked to Lung Squamous Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs4573350 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4573350 come from?

GWAS Catalog, Frontiers of medicine 2021, PMID:32889700. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Squamous cell lung carcinoma (rs4573350). MyGeneLog™. https://www.mygenelog.com/variants/rs4573350

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