RTDR1 · rs45608532
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 38,322 European ancestry left-handed individuals, 356,567 European ancestry right-handed individuals.
The effect Each copy of the A allele carried 1.09 times the odds of Handedness (left-handed vs. right-handed) (95% confidence interval 1.06-1.12); p = 1 × 10−8.
How common The A allele had a frequency of about 8% in the people studied.
Where it sits Chromosome 22, band 22q11.22 — in an intron of RSPH14.
rs45608532 is a single position in the genome, in or near the RTDR1 gene. Published research associates it with handedness (left-handed vs. right-handed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Brain : a journal of neurology 2019, PMID:31504236. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Handedness (left-handed vs. right-handed) (rs45608532). MyGeneLog™. https://www.mygenelog.com/variants/rs45608532