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Gut microbiota relative abundance (hMGS.01048: Coprobacillus cateniformis)

MUC12 · rs4556017

Where this position leads

Condition: Gut Microbiota

What the study found

Who was studied 12,652 European ancestry individuals; replicated in 21,976 European ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 1 × 10⁻³⁷.

Where it sits Chromosome 7, band 7q22.1 — in an intron of MUC12.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Gut microbiota relative abundance (hMGS.01048: Coprobacillus cateniformis) — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Gut microbiota relative abundance (hMGS.01048: Coprobacillus cateniformis).

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Gut microbiota relative abundance (hMGS.01048: Coprobacillus cateniformis) compared to the general population.

Source

The HUNT study identifies host genetic factors reproducibly associated with human gut microbiota composition

Moksnes MR, Coward E, Nethander M, Dekkers K, Grahnemo L, Törnqvist AE, Li L, Lundmark P, Pertiwi K, Baldanzi G, Mjelle R, Moll JM

and 15 more — show all

Eklund AC, Nielsen HB, Svensson J, Langhammer A, Giskeødegård GF, Brumpton B, Hjort R, Ness-Jensen E, Engström G, Pelaseyed T, Michaëlsson K, Orho-Melander M, Fall T, Hveem K, Ohlsson C

Nature genetics · 2026 · PMID 41688637 · open access

Questions about rs4556017

What is rs4556017?

rs4556017 is a single position in the genome, in or near the MUC12 gene. Published research associates it with gut microbiota relative abundance (hmgs.01048: coprobacillus cateniformis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4556017 linked to?

On MyGeneLog this position is linked to Gut Microbiota. The research behind each link, and its sources, are set out on that condition page.

Does having rs4556017 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4556017 come from?

GWAS Catalog, GWAS Catalog n.d., PMID:41688637. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Gut microbiota relative abundance (hMGS.01048: Coprobacillus cateniformis) (rs4556017). MyGeneLog™. https://www.mygenelog.com/variants/rs4556017

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