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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 95,827 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.14 higher (95% confidence interval 0.1-0.18); p = 4 × 10−9.
Where it sits Chromosome 11, band 11q23.3 — between genes, 0.2 kb from MFRP.
What each result means
C/CNo copy of the version the research linked to Spherical equivalent. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Spherical equivalent. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Spherical equivalent. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs45509899 is a single position in the genome, in or near the near MFRP gene. Published research associates it with spherical equivalent. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs45509899 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs45509899 come from?
GWAS Catalog, JAMA ophthalmology 2020, PMID:32352494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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