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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,020 Korculan or Shetland Isles (founder/genetic isolate) individuals.
The effect
Each copy of the T allele shifted the measure 0.195 lower (95% confidence interval 0.13-0.26); p = 2 × 10−9.
How common The T allele had a frequency of about 41% in the people studied.
Where it sits Chromosome 6, band 6q24.1 — between genes, 16.4 kb from TXLNB.
What each result means
C/CNo copy of the version the research linked to Immunoglobulin N-glycan 10 levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Immunoglobulin N-glycan 10 levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Immunoglobulin N-glycan 10 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2022 · PMID 35332118 · open access
Questions about rs4543384
What is rs4543384?
rs4543384 is a single position in the genome, in or near the near TXLNB gene. Published research associates it with immunoglobulin n-glycan 10 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4543384 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4543384 come from?
GWAS Catalog, Nature communications 2022, PMID:35332118. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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