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Intralaminar thalamic nuclei volume

BICD1 · rs4540912

What the study found

Who was studied 30,114 white British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.056 higher (95% confidence interval 0.039-0.074); p = 4 × 10−10.

How common The A allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 12, band 12p11.21 — in an intron of BICD1.

What each result means

A/A Two copies of the version the research linked to Intralaminar thalamic nuclei volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Intralaminar thalamic nuclei volume. That is a smaller link than two copies.
G/G No copy of the version the research linked to Intralaminar thalamic nuclei volume. This is the starting point the study compared everyone against.
Source

Questions about rs4540912

What is rs4540912?

rs4540912 is a single position in the genome, in or near the BICD1 gene. Published research associates it with intralaminar thalamic nuclei volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4540912 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4540912 come from?

GWAS Catalog, Nature communications 2021, PMID:34006833. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Intralaminar thalamic nuclei volume (rs4540912). MyGeneLog™. https://www.mygenelog.com/variants/rs4540912

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