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Added salt consumption

SATB1-AS1 · rs453585

What the study found

Who was studied 448,890 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0173 lower (95% confidence interval 0.013-0.022); p = 5 × 10−16.

How common The G allele had a frequency of about 38% in the people studied.

Where it sits Chromosome 3, band 3p24.3 — in an intron of SATB1-AS1.

What each result means

A/A No copy of the version the research linked to Added salt consumption. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Added salt consumption. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Added salt consumption. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs453585

What is rs453585?

rs453585 is a single position in the genome, in or near the SATB1-AS1 gene. Published research associates it with added salt consumption. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs453585 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs453585 come from?

GWAS Catalog, Nature communications 2020, PMID:32193382. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Added salt consumption (rs453585). MyGeneLog™. https://www.mygenelog.com/variants/rs453585

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