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Asthma

AHI1 · rs4526212

Where this position leads

Condition: Asthma

rs4526212 Condition: Asthma Asthma Condition rs4526212 rs4526212 AHI1

What the study found

Who was studied 84,492 European ancestry cases, 2,149 African American cases, 606 Hispanic cases, 1,239 Japanese ancestry cases, 437,036 European ancestry controls, 6,055 African American controls, 792 Hispanic controls, 3,976 Japanese ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−13.

How common The A allele had a frequency of about 37% in the people studied.

Where it sits Chromosome 6, band 6q23.3 — in an intron of AHI1.

What each result means

A/A Two copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Asthma. That is a smaller link than two copies.
C/C No copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
Source

Questions about rs4526212

What is rs4526212?

rs4526212 is a single position in the genome, in or near the AHI1 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4526212 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs4526212 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4526212 come from?

GWAS Catalog, Nat Commun 2020, PMID:32296059. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma (rs4526212). MyGeneLog™. https://www.mygenelog.com/variants/rs4526212

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