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Saturated fatty acid percentage of total fatty acids

RASIP1 · rs452270

What the study found

Who was studied 199,732 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0283 higher (95% confidence interval 0.022-0.034); p = 2 × 10−19.

How common The C allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 19, band 19q13.33 — in an intron of RASIP1.

What each result means

C/C Two copies of the version the research linked to Saturated fatty acid percentage of total fatty acids. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Saturated fatty acid percentage of total fatty acids. That is a smaller link than two copies.
T/T No copy of the version the research linked to Saturated fatty acid percentage of total fatty acids. This is the starting point the study compared everyone against.
Source

Questions about rs452270

What is rs452270?

rs452270 is a single position in the genome, in or near the RASIP1 gene. Published research associates it with saturated fatty acid percentage of total fatty acids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs452270 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs452270 come from?

GWAS Catalog, British journal of cancer 2025, PMID:40307439. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Saturated fatty acid percentage of total fatty acids (rs452270). MyGeneLog™. https://www.mygenelog.com/variants/rs452270

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