C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Prostate cancer compared to the general population. (GWAS Catalog, Hum Genet 2016, PMID:27262462)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Prostate cancer. (GWAS Catalog, Hum Genet 2016, PMID:27262462)
T/TPublished research associates this genotype with typical/baseline likelihood of Prostate cancer — no copies of the reported risk allele. (GWAS Catalog, Hum Genet 2016, PMID:27262462)
rs4506170 is a single position in the genome, in or near the CASC8 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4506170 linked to?
On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs4506170 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4506170 come from?
GWAS Catalog, Hum Genet 2016, PMID:27262462. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.