Standard

White matter connectivity (global efficiency)

LINC02210-CRHR1 · rs450237

What the study found

Who was studied 26,655 British ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0821 lower; p = 3 × 10−20.

How common The C allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 17, band 17q21.31 — in an intron of LINC02210-CRHR1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of White matter connectivity (global efficiency) compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with White matter connectivity (global efficiency).
T/T Published research associates this genotype with typical/baseline likelihood of White matter connectivity (global efficiency) — no copies of the reported risk allele.
Source

Questions about rs450237

What is rs450237?

rs450237 is a single position in the genome, in or near the LINC02210-CRHR1 gene. Published research associates it with white matter connectivity (global efficiency). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs450237 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs450237 come from?

GWAS Catalog, Communications biology 2026, PMID:42092107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

White matter connectivity (global efficiency) (rs450237). MyGeneLog™. https://www.mygenelog.com/variants/rs450237

← See all variants