0 131129Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others9Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 8,873 African American or Afro-Caribbean cases, 109,974 African American or Afro-Caribbean controls, 4,063 Hispanic or Latin American cases, 54,799 Hispanic or Latin American controls, 397 East Asian ancestry cases, 6,355 East Asian ancestry controls, 71,577 European ancestry cases, 366,195 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.0759 higher (95% confidence interval 0.059-0.093); p = 5 × 10−21.
How common The G allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 5, band 5q31.3 — between genes, 32.9 kb from NR3C1.
What each result means
A/ANo copy of the version the research linked to Atrial fibrillation (PheCode 427.21). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Atrial fibrillation (PheCode 427.21). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Atrial fibrillation (PheCode 427.21). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs4501370
What is rs4501370?
rs4501370 is a single position in the genome, in or near the near NR3C1 gene. Published research associates it with atrial fibrillation (phecode 427.21). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4501370 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs4501370 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4501370 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 131129Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others9Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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