C/CPublished research associates this genotype with typical/baseline likelihood of Itch intensity from mosquito bite adjusted by bite size — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Itch intensity from mosquito bite adjusted by bite size.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Itch intensity from mosquito bite adjusted by bite size compared to the general population.
Human molecular genetics · 2017 · PMID 28199695 · open access
Questions about rs4499342
What is rs4499342?
rs4499342 is a single position in the genome, in or near the ADAMTS10 gene. Published research associates it with itch intensity from mosquito bite adjusted by bite size. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4499342 linked to?
On MyGeneLog this position is linked to Mosquito Bite Reaction. The research behind each link, and its sources, are set out on that condition page.
Does having rs4499342 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4499342 come from?
GWAS Catalog, Hum Mol Genet 2017, PMID:28199695. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.