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Leukocyte telomere length

near NOL11 · rs4496196

What the study found

Who was studied 327,790 British ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.013 lower (95% confidence interval 0.0091-0.0169); p = 3 × 10−8.

How common The G allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 17, band 17q24.2 — between genes, 7.2 kb from NOL11.

What each result means

C/C No copy of the version the research linked to Leukocyte telomere length. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Leukocyte telomere length. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Leukocyte telomere length. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4496196

What is rs4496196?

rs4496196 is a single position in the genome, in or near the near NOL11 gene. Published research associates it with leukocyte telomere length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4496196 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4496196 come from?

GWAS Catalog, GeroScience 2024, PMID:38837026. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Leukocyte telomere length (rs4496196). MyGeneLog™. https://www.mygenelog.com/variants/rs4496196

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