Standard
Urinary uromodulin levels
PDILT · rs4494548
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Urinary uromodulin levels compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Urinary uromodulin levels.
G/G
Published research associates this genotype with typical/baseline likelihood of Urinary uromodulin levels — no copies of the reported risk allele.
Source
Common variants in UMOD associate with urinary uromodulin levels: a meta-analysis
Olden M,
Corre T,
Hayward C,
Toniolo D,
Ulivi S,
Gasparini P,
Pistis G,
Hwang SJ,
Bergmann S,
Campbell H,
Cocca M,
Gandin I
and 18 more — show all
Girotto G,
Glaudemans B,
Hastie ND,
Loffing J,
Polasek O,
Rampoldi L,
Rudan I,
Sala C,
Traglia M,
Vollenweider P,
Vuckovic D,
Youhanna S,
Weber J,
Wright AF,
Kutalik Z,
Bochud M,
Fox CS,
Devuyst O
Journal of the American Society of Nephrology : JASN · 2014 · PMID 24578125
Questions about rs4494548
What is rs4494548?
rs4494548 is a single position in the genome, in or near the PDILT gene. Published research associates it with urinary uromodulin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4494548 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4494548 come from?
GWAS Catalog, J Am Soc Nephrol 2014, PMID:24578125. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants