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Gut microbiota (bacterial taxa, hurdle binary method)

EXT2 · rs4494297

Where this position leads

Condition: Gut Microbiota

rs4494297 Condition: Gut Microbiota Gut Microbiota Condition rs4494297 rs4494297 EXT2

What the study found

Who was studied 2,223 European ancestry individuals; replicated in 1,667 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 1.94 lower (95% confidence interval 1.32-2.56); p = 7 × 10−10.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 11, band 11p11.2 — in an intron of EXT2.

What each result means

G/G No copy of the version the research linked to Gut microbiota (bacterial taxa, hurdle binary method). This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Gut microbiota (bacterial taxa, hurdle binary method). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Gut microbiota (bacterial taxa, hurdle binary method). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4494297

What is rs4494297?

rs4494297 is a single position in the genome, in or near the EXT2 gene. Published research associates it with gut microbiota (bacterial taxa, hurdle binary method). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4494297 linked to?

On MyGeneLog this position is linked to Gut Microbiota. The research behind each link, and its sources, are set out on that condition page.

Does having rs4494297 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4494297 come from?

GWAS Catalog, Nature microbiology 2020, PMID:32572223. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Gut microbiota (bacterial taxa, hurdle binary method) (rs4494297). MyGeneLog™. https://www.mygenelog.com/variants/rs4494297

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