Standard

Systolic blood pressure

LINC02227 · rs4490571

Where this position leads

Condition: Blood Pressure

rs4490571 Condition: Blood Pressure Blood Pressure Condition rs4490571 rs4490571 LINC02227

What the study found

Who was studied 286,581 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.378 lower (95% confidence interval 0.29-0.47); p = 3 × 10−11.

Where it sits Chromosome 5, band 5q33.3 — in an intron of LINC02227.

What each result means

A/A No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4490571

What is rs4490571?

rs4490571 is a single position in the genome, in or near the LINC02227 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4490571 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs4490571 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4490571 come from?

GWAS Catalog, Scientific reports 2024, PMID:39548300. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs4490571). MyGeneLog™. https://www.mygenelog.com/variants/rs4490571

← See all variants