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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 248,847 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.055 higher (95% confidence interval 0.041-0.069); p = 2 × 10−14.
How common The G allele had a frequency of about 44% in the people studied.
Where it sits Chromosome 5, band 5q14.3 — in an intron of MEF2C-AS2.
What each result means
G/GTwo copies of the version the research linked to Occupational attainment. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Occupational attainment. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Occupational attainment. This is the starting point the study compared everyone against.
Brain : a journal of neurology · 2022 · PMID 34613391
Questions about rs448809
What is rs448809?
rs448809 is a single position in the genome, in or near the MEF2C-AS2 gene. Published research associates it with occupational attainment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs448809 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs448809 come from?
GWAS Catalog, Brain : a journal of neurology 2022, PMID:34613391. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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