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Asparagus urine odour detection

OR2M7 · rs4481887

Where this position leads

Condition: Smell Perception and Specific Anosmias

Smell & taste: Specific Anosmias — a smell that is obvious to one person and simply absent for another

rs4481887 Condition: Smell Perception and Specific Anosmias Smell Perception and Specific Anosmias Condition Smell & taste: Specific Anosmias Specific Anosmias Smell & taste rs4481887 rs4481887 OR2M7

What each result means

A/A Two copies of the common allele. Published research associates this genotype with being able to smell the sulfur compounds that appear in urine after eating asparagus.
A/G One copy of the variant allele. Published research associates each copy of this allele with roughly 1.67 times higher odds of being unable to smell those compounds — a specific anosmia, meaning the sense of smell is normal for everything else.
G/G Two copies of the variant allele. Published research associates this genotype with the highest likelihood of not smelling anything unusual in urine after eating asparagus. Everyone produces the compounds; this is about whether you can detect them.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs4481887

What is rs4481887?

rs4481887 is a single position in the genome, in or near the OR2M7 gene. Published research associates it with asparagus urine odour detection. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4481887 linked to?

On MyGeneLog this position is linked to Smell Perception and Specific Anosmias. The research behind each link, and its sources, are set out on that condition page.

Does rs4481887 affect smell or taste?

This position sits in the Specific Anosmias group on the chemosensory axis. Chemosensory variants do not shift a risk — they change the perception itself, which makes them the rarest thing on this site: genetics you can check on yourself.

What do people read about alongside rs4481887?

Subjects that appear in the title or abstract of the same papers as this rsID include skin, sun and hair (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs4481887 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4481887 come from?

Eriksson et al. 2010, PLoS Genetics — web-based, participant-driven studies yield novel genetic associations for common traits (PMID 20585627); odds ratio 1.67 per G allele, p = 7 x 10^-24. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Asparagus urine odour detection (rs4481887). MyGeneLog™. https://www.mygenelog.com/variants/rs4481887-asparagus

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