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Who was studied 5,571 Chinese ancestry individuals; replicated in 2,981 Chinese ancestry individuals.
The effect
Each copy of the G allele shifted the measure 6.66 z score lower; p = 3 × 10−11.
How common The G allele had a frequency of about 8% in the people studied.
Where it sits Chromosome 15, band 15q11.2 — in a non-coding transcript of PWRN1.
What each result means
G/GTwo copies of the version the research linked to Intraocular pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Intraocular pressure. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Intraocular pressure. This is the starting point the study compared everyone against.
Science China. Life sciences · 2019 · PMID 30591961
Questions about rs4467035
What is rs4467035?
rs4467035 is a single position in the genome, in or near the PWRN2 gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4467035 linked to?
On MyGeneLog this position is linked to Intraocular Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs4467035 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4467035 come from?
GWAS Catalog, Science China. Life sciences 2019, PMID:30591961. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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