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Who was studied 257,841 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0218 higher (95% confidence interval 0.016-0.027); p = 3 × 10−14.
How common The A allele had a frequency of about 55% in the people studied.
Where it sits Chromosome 5, band 5q31.3 — between genes, 8.9 kb from CYSTM1.
What each result means
A/ATwo copies of the version the research linked to Cognitive performance. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Cognitive performance. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Cognitive performance. This is the starting point the study compared everyone against.
rs4463213 is a single position in the genome, in or near the near CYSTM1 gene. Published research associates it with cognitive performance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4463213 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does having rs4463213 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4463213 come from?
GWAS Catalog, Nature genetics 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1411228Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others8Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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