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Relative abundance of the human milk microbiota (HMM) Rothia kristinae

near UBE2K · rs4455428

What the study found

Who was studied 733 European ancestry, South Asian ancestry, East Asian ancestry, African American or Afro-Caribbean, Other admixed ancestry ancestry, Other ancestry females.

The effect Each copy of the T allele shifted the measure 0.546 higher (95% confidence interval 0.36-0.74); p = 2 × 10−8.

Where it sits Chromosome 4, band 4p14 — between genes, 6.5 kb from SMIM14-DT.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Relative abundance of the human milk microbiota (HMM) Rothia kristinae — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Relative abundance of the human milk microbiota (HMM) Rothia kristinae.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Relative abundance of the human milk microbiota (HMM) Rothia kristinae compared to the general population.
Source

Questions about rs4455428

What is rs4455428?

rs4455428 is a single position in the genome, in or near the near UBE2K gene. Published research associates it with relative abundance of the human milk microbiota (hmm) rothia kristinae. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4455428 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4455428 come from?

GWAS Catalog, Cell host & microbe 2024, PMID:39293435. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Relative abundance of the human milk microbiota (HMM) Rothia kristinae (rs4455428). MyGeneLog™. https://www.mygenelog.com/variants/rs4455428

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