0 272176137Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot6Amazon1Apple3China (ByteDance, Huawei, Baidu…)0Others7Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 449,484 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 5.67 z score lower (95% confidence interval -); p = 1 × 10−8.
Where it sits Chromosome 18, band 18q21.2 — in an intron of DCC.
What each result means
A/ATwo copies of the version the research linked to Neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Neuroticism. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Neuroticism. This is the starting point the study compared everyone against.
rs4453579 is a single position in the genome, in or near the DCC gene. Published research associates it with neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4453579 linked to?
On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.
Does having rs4453579 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4453579 come from?
GWAS Catalog, Nat Genet 2018, PMID:29942085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 272176137Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot6Amazon1Apple3China (ByteDance, Huawei, Baidu…)0Others7Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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