A/APublished research associates this genotype with typical/baseline likelihood of Reticulocyte fraction of red cells — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Reticulocyte fraction of red cells.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Reticulocyte fraction of red cells compared to the general population.
rs4434553 is a single position in the genome, in or near the TFR2 gene. Published research associates it with reticulocyte fraction of red cells. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4434553 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs4434553 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4434553 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.