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High light scatter reticulocyte count (UKB data field 30300)

LINC01524 · rs4431004

Where this position leads

Condition: Celiac Disease

rs4431004 Condition: Celiac Disease Celiac Disease Condition rs4431004 rs4431004 LINC01524

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.018 lower (95% confidence interval 0.014-0.022); p = 3 × 10−17.

How common The G allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 20, band 20q13.2 — in an intron of LINC01524.

What each result means

A/A No copy of the version the research linked to High light scatter reticulocyte count (UKB data field 30300). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to High light scatter reticulocyte count (UKB data field 30300). That is a smaller link than two copies.
G/G Two copies of the version the research linked to High light scatter reticulocyte count (UKB data field 30300). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4431004

What is rs4431004?

rs4431004 is a single position in the genome, in or near the LINC01524 gene. Published research associates it with high light scatter reticulocyte count (ukb data field 30300). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4431004 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs4431004 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4431004 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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High light scatter reticulocyte count (UKB data field 30300) (rs4431004). MyGeneLog™. https://www.mygenelog.com/variants/rs4431004

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