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Who was studied 516 Turkish ancestry cases, 119 European ancestry cases, 462 Turkish ancestry controls, 993 European ancestry controls.
The effect
Each copy of the G allele carried 3.52 times the odds of Takayasu arteritis (95% confidence interval 2.34-5.30); p = 2 × 10−10.
How common The G allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of PSORS1C1.
What each result means
A/ANo copy of the version the research linked to Takayasu arteritis. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Takayasu arteritis. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Takayasu arteritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs4410768 is a single position in the genome, in or near the CDSN gene. Published research associates it with takayasu arteritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4410768 linked to?
On MyGeneLog this position is linked to Takayasu Arteritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs4410768 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4410768 come from?
GWAS Catalog, Arthritis & rheumatology (Hoboken, N.J.) 2015, PMID:25604533. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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