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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 35,049 individuals.
The effect
Each copy of the T allele shifted the measure 0.056 higher (95% confidence interval 0.04-0.072); p = 7 × 10−14.
How common The T allele had a frequency of about 62% in the people studied.
Where it sits Chromosome 14, band 14q11.2 — in an intron of MYH6.
What each result means
C/CNo copy of the version the research linked to Left atrial emptying fraction. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Left atrial emptying fraction. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Left atrial emptying fraction. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 38773065 · open access
Questions about rs440466
What is rs440466?
rs440466 is a single position in the genome, in or near the MYH6 gene. Published research associates it with left atrial emptying fraction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs440466 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs440466 come from?
GWAS Catalog, Nature communications 2024, PMID:38773065. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Left atrial emptying fraction (rs440466). MyGeneLog™. https://www.mygenelog.com/variants/rs440466