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Who was studied 6,337 European ancestry cases, 61,607 European ancestry controls; replicated in 30,679 European ancestry cases, 278,895 European ancestry controls.
The effect
Each copy of the A allele carried 1.18 times the odds of Atrial fibrillation (95% confidence interval 1.12-1.24); p = 6 × 10−10.
How common The A allele had a frequency of about 16% in the people studied.
Where it sits Chromosome 16, band 16q22.3 — in an intron of ZFHX3.
What each result means
A/ATwo copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
American journal of human genetics · 2018 · PMID 29290336
Questions about rs4404097
What is rs4404097?
rs4404097 is a single position in the genome, in or near the ZHFX3 gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4404097 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs4404097 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4404097 come from?
GWAS Catalog, Am J Hum Genet 2018, PMID:29290336. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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