0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 14,296 European ancestry individuals; replicated in 5,698 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.123 lower (95% confidence interval 0.088-0.158); p = 6 × 10−12.
How common The C allele had a frequency of about 9% in the people studied.
Where it sits Chromosome 2, band 2q37.1 — between genes, 3.4 kb from UGT1A11P.
What each result means
C/CTwo copies of the version the research linked to X-21339 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to X-21339 levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to X-21339 levels. This is the starting point the study compared everyone against.
Nature medicine · 2022 · PMID 36357675 · open access
Questions about rs4402757
What is rs4402757?
rs4402757 is a single position in the genome, in or near the near UGT1A11P gene. Published research associates it with x-21339 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4402757 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4402757 come from?
GWAS Catalog, Nature medicine 2022, PMID:36357675. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.