0 6123Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 62,892 European ancestry T2D cases, 79,194 European ancestry PrCa cases, 659,536 European ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 1 × 10−15.
How common The A allele had a frequency of about 35% in the people studied.
Where it sits Chromosome 6, band 6q25.2 — in an intron of RGS17.
What each result means
A/ATwo copies of the version the research linked to Type 2 diabetes or prostate cancer (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Type 2 diabetes or prostate cancer (pleiotropy). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Type 2 diabetes or prostate cancer (pleiotropy). This is the starting point the study compared everyone against.
PLoS genetics · 2020 · PMID 33290408 · open access
Questions about rs4385321
What is rs4385321?
rs4385321 is a single position in the genome, in or near the RGS17 gene. Published research associates it with type 2 diabetes or prostate cancer (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4385321 linked to?
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs4385321 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4385321 come from?
GWAS Catalog, PLoS genetics 2020, PMID:33290408. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 6123Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 2 diabetes or prostate cancer (pleiotropy) (rs4385321). MyGeneLog™. https://www.mygenelog.com/variants/rs4385321