3 4723215123118Reads by AI crawlersClaude2ChatGPT3Google · Gemini0Perplexity2Meta AI15Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others18Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 286 European ancestry cases, 2,652 European ancestry controls, 76 Han Chinese ancestry cases, 889 Han Chinese ancestry controls, 46 South Asian ancestry cases, 501 South Asian ancestry controls, 683 Turkish ancestry cases, 1,721 Turkish ancestry controls.
The effect
Each copy of the T allele carried 1.36 times the odds of Takayasu arteritis; p = 3 × 10−9.
Where it sits Chromosome 5, band 5q33.3 — inside IL12B-AS1.
What each result means
G/GNo copy of the version the research linked to Takayasu arteritis. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Takayasu arteritis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Takayasu arteritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2021 · PMID 33308445
Questions about rs4379175
What is rs4379175?
rs4379175 is a single position in the genome, in or near the IL12B gene. Published research associates it with takayasu arteritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4379175 linked to?
On MyGeneLog this position is linked to Takayasu Arteritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs4379175 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4379175 come from?
GWAS Catalog, Am J Hum Genet 2020, PMID:33308445. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 4723215123118Reads by AI crawlersClaude2ChatGPT3Google · Gemini0Perplexity2Meta AI15Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others18Total47Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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