1 201123211Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others11Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 8,873 African American or Afro-Caribbean cases, 109,974 African American or Afro-Caribbean controls, 4,063 Hispanic or Latin American cases, 54,799 Hispanic or Latin American controls, 397 East Asian ancestry cases, 6,355 East Asian ancestry controls, 71,577 European ancestry cases, 366,195 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.0506 higher (95% confidence interval 0.037-0.064); p = 5 × 10−14.
How common The G allele had a frequency of about 45% in the people studied.
Where it sits Chromosome 2, band 2q31.1 — in an intron of WIPF1.
What each result means
G/GTwo copies of the version the research linked to Atrial fibrillation (PheCode 427.21). That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Atrial fibrillation (PheCode 427.21). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Atrial fibrillation (PheCode 427.21). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs4378760
What is rs4378760?
rs4378760 is a single position in the genome, in or near the WIPF1 gene. Published research associates it with atrial fibrillation (phecode 427.21). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4378760 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs4378760 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4378760 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 201123211Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others11Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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