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Neuroticism

near DRD2 · rs4373974

Where this position leads

Condition: Neuroticism

rs4373974 Condition: Neuroticism Neuroticism Condition rs4373974 rs4373974 near DRD2

What the study found

Who was studied 449,484 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 6.33 z score higher (95% confidence interval -); p = 3 × 10−10.

Where it sits Chromosome 11, band 11q23.2 — between genes, 26.6 kb from LOC107984390.

What each result means

G/G No copy of the version the research linked to Neuroticism. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Neuroticism. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4373974

What is rs4373974?

rs4373974 is a single position in the genome, in or near the near DRD2 gene. Published research associates it with neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4373974 linked to?

On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.

Does having rs4373974 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4373974 come from?

GWAS Catalog, Nat Genet 2018, PMID:29942085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Neuroticism (rs4373974). MyGeneLog™. https://www.mygenelog.com/variants/rs4373974

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