0 81214Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others4Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 20,406 European ancestry cases, 223,918 European ancestry controls; replicated in 15,068 European ancestry cases, 43,587 European ancestry controls.
The effect
Each copy of the A allele carried 1.08 times the odds of Uterine fibroids (95% confidence interval 1.06-1.10); p = 2 × 10−18.
How common The A allele had a frequency of about 37% in the people studied.
Where it sits Chromosome X, band Xq13.1 — a synonymous change in SLC7A3.
What each result means
A/ATwo copies of the version the research linked to Uterine fibroids. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Uterine fibroids. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Uterine fibroids. This is the starting point the study compared everyone against.
Nature communications · 2019 · PMID 31649266 · open access
Questions about rs4360450
What is rs4360450?
rs4360450 is a single position in the genome, in or near the MED12 gene. Published research associates it with uterine fibroids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4360450 linked to?
On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.
Does having rs4360450 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4360450 come from?
GWAS Catalog, Nature communications 2019, PMID:31649266. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 81214Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others4Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.