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Putamen iron levels (R2* MRI)

near MAF · rs434626

What the study found

Who was studied 39,533 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0669 higher (95% confidence interval 0.053-0.081); p = 2 × 10−23.

Where it sits Chromosome 16, band 16q23.2 — between genes, 13.2 kb from MAF.

What each result means

C/C Two copies of the version the research linked to Putamen iron levels (R2* MRI). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Putamen iron levels (R2* MRI). That is a smaller link than two copies.
T/T No copy of the version the research linked to Putamen iron levels (R2* MRI). This is the starting point the study compared everyone against.
Source

Questions about rs434626

What is rs434626?

rs434626 is a single position in the genome, in or near the near MAF gene. Published research associates it with putamen iron levels (r2* mri). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs434626 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs434626 come from?

GWAS Catalog, Neurobiology of disease 2024, PMID:38789058. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Putamen iron levels (R2* MRI) (rs434626). MyGeneLog™. https://www.mygenelog.com/variants/rs434626

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