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Medication use (glucocorticoids)

near EEF1A1P27 · rs4335039

What the study found

Who was studied 17,352 European ancestry cases, 188,348 European ancestry controls, 13,102 East Asian ancestry cases, 165,624 East Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0527 lower (95% confidence interval 0.035-0.07); p = 4 × 10−9.

Where it sits Chromosome 7, band 7p21.1 — between genes, 39.7 kb from EEF1A1P27.

What each result means

A/A Two copies of the version the research linked to Medication use (glucocorticoids). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Medication use (glucocorticoids). That is a smaller link than two copies.
T/T No copy of the version the research linked to Medication use (glucocorticoids). This is the starting point the study compared everyone against.
Source

Questions about rs4335039

What is rs4335039?

rs4335039 is a single position in the genome, in or near the near EEF1A1P27 gene. Published research associates it with medication use (glucocorticoids). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4335039 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4335039 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Medication use (glucocorticoids) (rs4335039). MyGeneLog™. https://www.mygenelog.com/variants/rs4335039

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