Standard
Uric acid levels
near DUSP9 · rs4328011
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 24,014 African ancestry males, 302,655 European ancestry males, 66,558 East Asian ancestry males.
The effect
Each copy of the A allele shifted the measure 0.0107 higher (95% confidence interval 0.0082-0.0131); p = 1 × 10−17.
How common The A allele had a frequency of about 54% in the people studied.
Where it sits Chromosome X, band Xq28 — between genes, 9.6 kb from DUSP9.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Uric acid levels compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Uric acid levels.
G/G
Published research associates this genotype with typical/baseline likelihood of Uric acid levels — no copies of the reported risk allele.
Source
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements
Scholz M,
Horn K,
Pott J,
Wuttke M,
Kühnapfel A,
Nasr MK,
Kirsten H,
Li Y,
Hoppmann A,
Gorski M,
Ghasemi S,
Li M
and 147 more — show all
Tin A,
Chai JF,
Cocca M,
Wang J,
Nutile T,
Akiyama M,
Åsvold BO,
Bansal N,
Biggs ML,
Boutin T,
Brenner H,
Brumpton B,
Burkhardt R,
Cai J,
Campbell A,
Campbell H,
Chalmers J,
Chasman DI,
Chee ML,
Chee ML,
Chen X,
Cheng CY,
Cifkova R,
Daviglus M,
Delgado G,
Dittrich K,
Edwards TL,
Endlich K,
Michael Gaziano J,
Giri A,
Giulianini F,
Gordon SD,
Gudbjartsson DF,
Hallan S,
Hamet P,
Hartman CA,
Hayward C,
Heid IM,
Hellwege JN,
Holleczek B,
Holm H,
Hutri-Kähönen N,
Hveem K,
Isermann B,
Jonas JB,
Joshi PK,
Kamatani Y,
Kanai M,
Kastarinen M,
Khor CC,
Kiess W,
Kleber ME,
Körner A,
Kovacs P,
Krajcoviechova A,
Kramer H,
Krämer BK,
Kuokkanen M,
Kähönen M,
Lange LA,
Lash JP,
Lehtimäki T,
Li H,
Lin BM,
Liu J,
Loeffler M,
Lyytikäinen LP,
Magnusson PKE,
Martin NG,
Matsuda K,
Milaneschi Y,
Mishra PP,
Mononen N,
Montgomery GW,
Mook-Kanamori DO,
Mychaleckyj JC,
März W,
Nauck M,
Nikus K,
Nolte IM,
Noordam R,
Okada Y,
Olafsson I,
Oldehinkel AJ,
Penninx BWJH,
Perola M,
Pirastu N,
Polasek O,
Porteous DJ,
Poulain T,
Psaty BM,
Rabelink TJ,
Raffield LM,
Raitakari OT,
Rasheed H,
Reilly DF,
Rice KM,
Richmond A,
Ridker PM,
Rotter JI,
Rudan I,
Sabanayagam C,
Salomaa V,
Schneiderman N,
Schöttker B,
Sims M,
Snieder H,
Stark KJ,
Stefansson K,
Stocker H,
Stumvoll M,
Sulem P,
Sveinbjornsson G,
Svensson PO,
Tai ES,
Taylor KD,
Tayo BO,
Teren A,
Tham YC,
Thiery J,
Thio CHL,
Thomas LF,
Tremblay J,
Tönjes A,
van der Most PJ,
Vitart V,
Völker U,
Wang YX,
Wang C,
Wei WB,
Whitfield JB,
Wild SH,
Wilson JF,
Winkler TW,
Wong TY,
Woodward M,
Sim X,
Chu AY,
Feitosa MF,
Thorsteinsdottir U,
Hung AM,
Teumer A,
Franceschini N,
Parsa A,
Köttgen A,
Schlosser P,
Pattaro C
Nature communications · 2024 · PMID 38233393 · open access
Questions about rs4328011
What is rs4328011?
rs4328011 is a single position in the genome, in or near the near DUSP9 gene. Published research associates it with uric acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4328011 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4328011 come from?
GWAS Catalog, Nature communications 2024, PMID:38233393. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Uric acid levels (rs4328011). MyGeneLog™. https://www.mygenelog.com/variants/rs4328011
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