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Who was studied 257,700 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0533 higher (95% confidence interval 0.038-0.069); p = 9 × 10−12.
How common The A allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 17, band 17q21.31 — in an intron of MAPT-AS1.
What each result means
A/ATwo copies of the version the research linked to Cognitive aspects of educational attainment. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Cognitive aspects of educational attainment. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Cognitive aspects of educational attainment. This is the starting point the study compared everyone against.
Nature genetics · 2021 · PMID 33414549 · open access
Questions about rs4327090
What is rs4327090?
rs4327090 is a single position in the genome, in or near the MAPT-AS1 gene. Published research associates it with cognitive aspects of educational attainment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4327090 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does having rs4327090 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4327090 come from?
GWAS Catalog, Nature genetics 2021, PMID:33414549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 1512111Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others11Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cognitive aspects of educational attainment (rs4327090). MyGeneLog™. https://www.mygenelog.com/variants/rs4327090