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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,006 Erasmus Rucphen Family (founder/genetic isolate) individuals, 26,692 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 8.12 lower (95% confidence interval 5.68-10.56); p = 7 × 10−11.
How common The A allele had a frequency of about 25% in the people studied.
Where it sits Chromosome 14, band 14q11.2 — in an intron of MYH6.
What each result means
A/ATwo copies of the version the research linked to RR interval (heart rate). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to RR interval (heart rate). That is a smaller link than two copies.
G/GNo copy of the version the research linked to RR interval (heart rate). This is the starting point the study compared everyone against.
European journal of human genetics : EJHG · 2019 · PMID 30679814 · open access
Questions about rs432256
What is rs432256?
rs432256 is a single position in the genome, in or near the MYH6 gene. Published research associates it with rr interval (heart rate). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs432256 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs432256 come from?
GWAS Catalog, Eur J Hum Genet 2019, PMID:30679814. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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