Sensitive

Kunitz-type protease inhibitor 2 level in Chronic kidney disease with hypertension and no diabetes (2843_13)

YIF1B · rs4312417

What the study found

Who was studied 466 African American individuals.

The effect Each copy of the G allele shifted the measure 0.57 lower (95% confidence interval 0.43-0.71); p = 7 × 10−17.

How common The G allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 19, band 19q13.2 — in an intron of YIF1B.

What each result means

A/A No copy of the version the research linked to Kunitz-type protease inhibitor 2 level in Chronic kidney disease with hypertension and no diabetes (2843_13). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Kunitz-type protease inhibitor 2 level in Chronic kidney disease with hypertension and no diabetes (2843_13). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Kunitz-type protease inhibitor 2 level in Chronic kidney disease with hypertension and no diabetes (2843_13). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4312417

What is rs4312417?

rs4312417 is a single position in the genome, in or near the YIF1B gene. Published research associates it with kunitz-type protease inhibitor 2 level in chronic kidney disease with hypertension and no diabetes (2843_13). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4312417 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4312417 come from?

GWAS Catalog, Kidney international 2022, PMID:35870639. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Kunitz-type protease inhibitor 2 level in Chronic kidney disease with hypertension and no diabetes (2843_13) (rs4312417). MyGeneLog™. https://www.mygenelog.com/variants/rs4312417

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